FEM-PRO 59.5: Unparalleled Support for Female Health and Well-Being

By: Ana Reisdorf, MS, RD

In any health assessment, after gathering general information, I always start by asking questions about gut health. I do this because even if you don’t have any digestive issues, health begins in the gut. But true health encompasses the whole body, so once the gut is handled, we have to tackle all other areas.

Probiotics are frequently recommended for gut health, but their benefits can go away beyond digestion. FEM-PRO 59.5 by Doctor’s Pick is a probiotic designed specifically for women’s total health to address the most common concerns women face, such as hormonal balance, skin health, weight management, and energy. It is also the only probiotic supplement on the market with saffron, which can help with mood, stress and anxiety.

FEM-PRO 59.9: More than Digestive Health

Your microbiome is not just limited to the gut. There are millions of bacterial species living on every part of your body, playing a role in every aspect of your health. FEM-PRO 59.5 contains a variety of probiotics to tackle every area of a woman’s health. It contains 17 different strains in optimal ratios to support mental, hormonal, immune, heart, and vaginal health.

Ingredients in FEM-PRO 59.5

The 17 strains in FEM-PRO 59.5 are all backed by clinical research to address common health concerns. These include:

To keep the bacteria healthy and help your body make the most of the supplement, these bacteria need food. FEM-PRO 59.5 contains a patent-pending organic prebiotic called Inubio™, which is a collection of organic whole food sources of fiber from inulin, chicory root, and Jerusalem artichoke. This type of fiber is not digested, therefore it is able to make its way to the colon to feed the healthy bacteria, while inhibiting the growth of bad bacteria. Aside from feeding bacteria, undigestible fiber has its own benefits such as lowering blood sugar, improving digestion, suppressing inflammation, and helping maintain a healthy weight.

FEM-PRO 59.5 also contains saffron, an aromatic spice that has been evaluated in multiple clinical studies to improve mood, manage symptoms of PMS, and help optimize brain function.

Not All Probiotics Are Created Equal

Have you ever taken a probiotic for several months, only to experience unpleasant side effects or no effects at all? That is because many probiotic formulas are loaded with cheaper probiotic strains (usually L acidophilus), and use only trace amounts of the more effective (and more expensive) strains. This is why so many probiotic formulas say their formula is “proprietary”—they hide the fact they’re mostly using the cheapest strains by not showing the amount of each probiotic strain that is actually in the formula.

In contrast, FEM-PRO 59.5, shows the exact amounts of each probiotic strain. You should know what you are putting in your body.

Another issue is that many probiotics contain artificial sweeteners or other fillers. These ingredients either have no effect on your health or as in the case of sweeteners, can negatively impact your body’s natural microbiome. FEM-PRO 59.5, on the other hand, contains no artificial sweeteners or fillers of any kind.

FEM-PRO 59.5 was carefully designed to optimize women’s health. Its carefully selected 17 strains hep address the most common concerns women have from mood to immunity to skin health. You deserve the best for your health. FEM-PRO 59.5 can help you reach your goals.

References

L. acidophilus
  1. Hong Y-F, Kim H, Kim HS, Park WJ, Kim J-Y, Chung DK. Lactobacillus acidophilus K301 Inhibits Atherogenesis via Induction of 24 (S), 25-Epoxycholesterol-Mediated ABCA1 and ABCG1 Production and Cholesterol Efflux in Macrophages. PLoS One. 2016;11(4):e0154302.
  2. Mastromarino P, Macchia S, Meggiorini L, et al. Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis. Clin Microbiol Infect. 2009;15(1):67-74.
  3. Chen L, Liu W, Li Y, et al. Lactobacillus acidophilus ATCC 4356 attenuates the atherosclerotic progression through modulation of oxidative stress and inflammatory process. Int Immunopharmacol. 2013;17(1):108-115.
L. bulgaricus
  1. Yu Q, Zhu L, Wang Z, Li P, Yang Q. Lactobacillus delbrueckii ssp. lactis R4 prevents Salmonella typhimurium SL1344-induced damage to tight junctions and adherens junctions. J Microbiol. 2012;50(4):613-617.
  2. Moro-García MA, Alonso-Arias R, Baltadjieva M, et al. Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects. Age . 2013;35(4):1311-1326.
L. casei
  1. Kato-Kataoka A, Nishida K, Takada M, et al. Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress. Benef Microbes. 2016;7(2):153-156.
  2. Alipour B, Homayouni-Rad A, Vaghef-Mehrabany E, et al. Effects of Lactobacillus casei supplementation on disease activity and inflammatory cytokines in rheumatoid arthritis patients: a randomized double-blind clinical trial. Int J Rheum Dis. 2014;17(5):519-527.
  3. Hwang JW, Baek Y-M, Yang KE, et al. Lactobacillus casei extract induces apoptosis in gastric cancer by inhibiting NF-κB and mTOR-mediated signaling. Integr Cancer Ther. 2013;12(2):165-173.
  4. Hill D, Sugrue I, Tobin C, Hill C, Stanton C, Ross RP. The Lactobacillus casei Group: History and Health Related Applications. Front Microbiol. 2018;9:2107.
L. Fermentum
  1. Cox AJ, Pyne DB, Saunders PU, Fricker PA. Oral administration of the probiotic Lactobacillus fermentum VRI-003 and mucosal immunity in endurance athletes. Br J Sports Med. 2010;44(4):222-226.
  2. Pan DD, Zeng XQ, Yan YT. Characterisation of Lactobacillus fermentum SM-7 isolated from koumiss, a potential probiotic bacterium with cholesterol-lowering effects. J Sci Food Agric. 2011;91(3):512-518.
  3. Mikelsaar M, Zilmer M. Lactobacillus fermentum ME-3 – an antimicrobial and antioxidative probiotic. Microb Ecol Health Dis. 2009;21(1):1-27.
L. gasseri
  1. Kadooka Y et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomized controlled trial. Br J Nutr. 2013 Nov 14;110(9):1696-703.Epub 2013 Apr 25
  2. Miyoshi M et al. Anti-obesity effect of Lactobacillus gasseri SBT2055 accompanied by inhibition of pro-inflammatory gene expression in the visceral adipose tissue in diet-induced obese mice.Eur J Nutr. 2014;53(2):599-606. doi: 10.1007/s00394-013-0568-9. Epub 2013 Aug 6.
  3. Miyazawa K, Kawase M, Kubota A, et al. Heat-killed Lactobacillus gasseri can enhance immunity in the elderly in a double-blind, placebo-controlled clinical study. Benef Microbes. 2015;6(4):441-449.
L. helveticus
  1. Liang S, Wang T, Hu X, et al. Administration of Lactobacillus helveticus NS8 improves behavioral, cognitive, and biochemical aberrations caused by chronic restraint stress. Neuroscience. 2015;310:561-577.
  2. Messaoudi M, Lalonde R, Violle N, et al. Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Br J Nutr. 2011;105(5):755-764.
L. plantarum
  1. Nishimura M, Ohkawara T, Tetsuka K, et al. Effects of yogurt containing Lactobacillus plantarum HOKKAIDO on immune function and stress markers. Afr J Tradit Complement Altern Med. 2016;6(3):275-280.
  2. Ferreira Dos Santos T, Alves Melo T, Almeida ME, Passos Rezende R, Romano CC. Immunomodulatory Effects of Lactobacillus plantarum Lp62 on Intestinal Epithelial and Mononuclear Cells. Biomed Res Int. 2016;2016:8404156.
L. reuteri
  1. Chew SY, Cheah YK, Seow HF, Sandai D, Than LTL. Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 exhibit strong antifungal effects against vulvovaginal candidiasis-causing Candida glabrata isolates. J Appl Microbiol. 2015;118(5):1180-1190.
  2. Mu Q, Tavella VJ, Luo XM. Role of Lactobacillus reuteri in Human Health and Diseases. Front Microbiol. 2018;9:757.
L. rhamnosus
  1. Recine N, Palma E, Domenici L, et al. Restoring vaginal microbiota: biological control of bacterial vaginosis. A prospective case-control study using Lactobacillus rhamnosus BMX 54 as adjuvant treatment against bacterial vaginosis. Arch Gynecol Obstet. 2016;293(1):101-107.
  2. Szajewska H, Kołodziej M. Systematic review with meta-analysis: Lactobacillus rhamnosus GG in the prevention of antibiotic-associated diarrhoea in children and adults. Aliment Pharmacol Ther. 2015;42(10):1149-1157.
  3. Fabbrocini G, Bertona M, Picazo Ó, Pareja-Galeano H, Monfrecola G, Emanuele E. Supplementation with Lactobacillus rhamnosus SP1 normalises skin expression of genes implicated in insulin signalling and improves adult acne. Benef Microbes. 2016;7(5):625-630.
  4. Sanchez M, Darimont C, Drapeau V, et al. Effect of Lactobacillus rhamnosus CGMCC1.3724 supplementation on weight loss and maintenance in obese men and women. Br J Nutr. 2014;111(8):1507-1519.
  5. Segers ME, Lebeer S. Towards a better understanding of Lactobacillus rhamnosus GG–host interactions. Microb Cell Fact. 2014;13 Suppl 1:S7.
B. bifidum
  1. Pugh JN, Sparks AS, Doran DA, et al. Four weeks of probiotic supplementation reduces GI symptoms during a marathon race. Eur J Appl Physiol. 2019;119(7):1491-1501.
  2. Langkamp-Henken B, Rowe CC, Ford AL, et al. Bifidobacterium bifidum R0071 results in a greater proportion of healthy days and a lower percentage of academically stressed students reporting a day of cold/flu: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2015;113(3):426-434.
  3. Tajabadi-Ebrahimi M, Sharifi N, Farrokhian A, et al. A Randomized Controlled Clinical Trial Investigating the Effect of Synbiotic Administration on Markers of Insulin Metabolism and Lipid Profiles in Overweight Type 2 Diabetic Patients with Coronary Heart Disease. Exp Clin Endocrinol Diabetes. 2017;125(1):21-27.
B. breve
  1. Kano M, Masuoka N, Kaga C, et al. Consecutive Intake of Fermented Milk Containing Bifidobacterium breve Strain Yakult and Galacto-oligosaccharides Benefits Skin Condition in Healthy Adult Women. Biosci Microbiota Food Health. 2013;32(1):33-39.
  2. Mori N, Kano M, Masuoka N, et al. Effect of probiotic and prebiotic fermented milk on skin and intestinal conditions in healthy young female students. Biosci Microbiota Food Health. 2016;35(3):105-112.
B. coagulans
  1. Taghizadeh M, Hashemi T, Shakeri H, et al. Synbiotic food consumption reduces levels of triacylglycerols and VLDL, but not cholesterol, LDL, or HDL in plasma from pregnant women. Lipids. 2014;49(2):155-161.
  2. Tajadadi-Ebrahimi M, Bahmani F, Shakeri H, et al. Effects of daily consumption of synbiotic bread on insulin metabolism and serum high-sensitivity C-reactive protein among diabetic patients: a double-blind, randomized, controlled clinical trial. Ann Nutr Metab. 2014;65(1):34-41.
  3. Rogha M, Esfahani MZ, Zargarzadeh AH. The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial. Gastroenterol Hepatol Bed Bench. 2014;7(3):156-163.
  4. Ratna Sudha M, Yelikar KA, Deshpande S. Clinical Study of Bacillus coagulans Unique IS-2 (ATCC PTA-11748) in the Treatment of Patients with Bacterial Vaginosis. Indian J Microbiol. 2012;52(3):396-399.
B. infantis
  1. You J, Yaqoob P. Evidence of immunomodulatory effects of a novel probiotic, Bifidobacterium longum bv. infantis CCUG 52486. FEMS Immunol Med Microbiol. 2012;66(3):353-362.
  2. Huang R, Wang K, Hu J. Effect of Probiotics on Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2016;8(8). doi:10.3390/nu8080483
  3. Whorwell PJ, Altringer L, Morel J, et al. Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome. Am J Gastroenterol. 2006;101(7):1581-1590.
B. lactis
  1. Bernini LJ, Simão ANC, Alfieri DF, et al. Beneficial effects of Bifidobacterium lactis on lipid profile and cytokines in patients with metabolic syndrome: A randomized trial. Effects of probiotics on metabolic syndrome. Nutrition. 2016;32(6):716-719.
  2. Waitzberg DL, Quilici FA, Michzputen S, Friche Passos M do C. THE EFFECT OF PROBIOTIC FERMENTED MILK THAT INCLUDES BIFIDOBACTERIUM LACTIS CNCM I-2494 ON THE REDUCTION OF GASTROINTESTINAL DISCOMFORT AND SYMPTOMS IN ADULTS: A NARRATIVE REVIEW. Nutr Hosp. 2015;32(2):501-509.
  3. Matsumoto M, Benno Y. Anti-inflammatory metabolite production in the gut from the consumption of probiotic yogurt containing Bifidobacterium animalis subsp. lactis LKM512. Biosci Biotechnol Biochem. 2006;70(6):1287-1292.
B. longum
  1. Akatsu H, Iwabuchi N, Xiao J-Z, et al. Clinical effects of probiotic Bifidobacterium longum BB536 on immune function and intestinal microbiota in elderly patients receiving enteral tube feeding. JPEN J Parenter Enteral Nutr. 2013;37(5):631-640.
  2. Xiao JZ, Kondo S, Takahashi N, et al. Effects of milk products fermented by Bifidobacterium longum on blood lipids in rats and healthy adult male volunteers. J Dairy Sci. 2003;86(7):2452-2461.
  3. Namba K, Hatano M, Yaeshima T, Takase M, Suzuki K. Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly. Biosci Biotechnol Biochem. 2010;74(5):939-945.
B. subtilis
  1. Liu Y-P, Liu X, Dong L. [Lactulose plus live binary Bacillus subtilis in the treatment of elders with functional constipation]. Zhonghua Yi Xue Za Zhi. 2012;92(42):2961-2964.
S. boulardii
  1. Akbari E, Asemi Z, Daneshvar Kakhaki R, et al. Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer’s Disease: A Randomized, Double-Blind and Controlled Trial. Front Aging Neurosci. 2016;8:256.
  2. Kelesidis T, Pothoulakis C. Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders. Therap Adv Gastroenterol. 2012;5(2):111-125.
Saffron
  1. Rajabian A, Hosseini A, Hosseini M, Sadeghnia HR. A Review of Potential Efficacy of Saffron (Crocus sativus L.) in Cognitive Dysfunction and Seizures. Prev Nutr Food Sci. 2019;24(4):363-372.
  2. Agha-Hosseini M, Kashani L, Aleyaseen A, et al. Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial. BJOG. 2008;115(4):515-519.
  3. Khazdair MR, Boskabady MH, Hosseini M, Rezaee R, M Tsatsakis A. The effects of Crocus sativus (saffron) and its constituents on nervous system: A review. Avicenna J Phytomed. 2015;5(5):376-391.
Prebiotics
  1. Liu F, Prabhakar M, Ju J, Long H, Zhou H-W. Effect of inulin-type fructans on blood lipid profile and glucose level: a systematic review and meta-analysis of randomized controlled trials. Eur J Clin Nutr. 2017;71(1):9-20.
  2. Nicolucci AC, Hume MP, Martínez I, Mayengbam S, Walter J, Reimer RA. Prebiotics Reduce Body Fat and Alter Intestinal Microbiota in Children Who Are Overweight or With Obesity. Gastroenterology. 2017;153(3):711-722.
  3. Watson AW, Houghton D, Avery PJ, et al. Changes in stool frequency following chicory inulin consumption, and effects on stool consistency, quality of life and composition of gut microbiota. Food Hydrocoll. 2019;96:688-698.
 

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THE 15 TOP CLINICALLY STUDIED PROBIOTIC STRAINS IN DOCTORS PICK BROAD PRO

(References at bottom of page: Most studies cited here were conducted on humans; only a relatively few listed involve lab animals.)
Doctors Pick BROAD PRO brings the best science has to offer

References:

 

Lactobacillus Acidophilus
  1. https://www.cancer.gov/publications/dictionaries/cancer-drug/def/probiotic-acidophilus
  2. https://www.ncbi.nlm.nih.gov/pubmed/8551535
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847857/
  4. https://www.ncbi.nlm.nih.gov/pubmed/23747589
  5. https://www.ncbi.nlm.nih.gov/pubmed/10067658
  6. https://www.journalofdairyscience.org/article/S0022-0302(10)00545-X/fulltext
  7. https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)60601-7/fulltext

 

Lactobacillus Bulgaricus
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705123/
  2. https://www.ncbi.nlm.nih.gov/pubmed/21986509
  3. https://www.ncbi.nlm.nih.gov/pubmed/20487575
  4. https://www.ncbi.nlm.nih.gov/pubmed/22923109
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680912/
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475728/
  7. https://www.ncbi.nlm.nih.gov/pubmed/8432622
  8. https://www.ncbi.nlm.nih.gov/pubmed/10660098
  9. https://www.ncbi.nlm.nih.gov/pubmed/597607
  10. https://www.ncbi.nlm.nih.gov/pubmed/3564372

 

Lactobacillus Casei:
  1. https://www.ncbi.nlm.nih.gov/pubmed/26419583
  2. https://www.ncbi.nlm.nih.gov/pubmed/26689231
  3. https://www.ncbi.nlm.nih.gov/pubmed/24673738
  4. https://www.ncbi.nlm.nih.gov/pubmed/20838859
  5. https://www.ncbi.nlm.nih.gov/pubmed/21810608
  6. https://www.ncbi.nlm.nih.gov/pubmed/26672414
  7. https://www.ncbi.nlm.nih.gov/pubmed/22505595
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743185/
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744000/
  10. https://www.ncbi.nlm.nih.gov/pubmed/23992486
  11. https://www.ncbi.nlm.nih.gov/pubmed/21329565
  12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858332/
  13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160870/#B55

 

Lactobacillus Fermentum:
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670518/
  2. https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.4214
  3. https://www.ncbi.nlm.nih.gov/pubmed/21218486
  4. https://www.sciencedirect.com/science/article/abs/pii/S0899900707000111?via%3Dihub
  5. https://www.ncbi.nlm.nih.gov/pubmed/27447674
  6. https://www.karger.com/Article/Abstract/328512
  7. https://bjsm.bmj.com/content/44/4/222

 

Lactobacillus Gasseri:

38. https://www.ncbi.nlm.nih.gov/pubmed/20216555

  1. https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effect-of-lactobacillus-gasseri-sbt2055-in-fermented-milk-on-abdominal-adiposity-in-adults-in-a-randomised-controlled-trial/304E3E2EE11E0D3D4F5D85E7046118A1
  2. Kadooka Y et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomized controlled trial. Br J Nutr. 2013 Nov 14;110(9):1696-703.Epub 2013 Apr 25
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391304/
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611107/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391304/
  6. Miyoshi M et al. Anti-obesity effect of Lactobacillus gasseri SBT2055 accompanied by inhibition of pro-inflammatory gene expression in the visceral adipose tissue in diet-induced obese mice.Eur J Nutr. 2014;53(2):599-606. doi: 10.1007/s00394-013-0568-9. Epub 2013 Aug 6.
  7. https://link.springer.com/article/10.1007%2Fs00203-015-1101-8
  8. https://www.wageningenacademic.com/doi/10.3920/BM2014.0108

 

Lactobacillus Plantarum:
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594053/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419998/
  3. https://www.researchgate.net/publication/304663353_Immunomodulatory_Effects_of_Lactobacillus_plantarum_Lp62_on_Intestinal_Epithelial_and_Mononuclear_Cells
  4. https://www.ncbi.nlm.nih.gov/pubmed/25598393
  5. https://www.ncbi.nlm.nih.gov/pubmed/26620542
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882673/
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936756/

 

Lactobacillus Reuteri:
  1. https://www.nature.com/articles/ejcn2012126
  2. https://www.ncbi.nlm.nih.gov/pubmed/22067612
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917019/
  4. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1348-0421.2009.00154.x
  5. https://www.ncbi.nlm.nih.gov/pubmed/25688886
  6. https://www.nature.com/articles/ejcn2012126
  7. https://www.ncbi.nlm.nih.gov/pubmed/25531996
  8. https://www.ncbi.nlm.nih.gov/pubmed/15629974
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813596/
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219330/
  11. https://www.omicsonline.org/open-access/beneficial-bacteria-stimulate-youthful-thyroid-gland-activity-2165-7904.1000220.php?aid=26919
  12. https://www.ncbi.nlm.nih.gov/pubmed/19895848

 

Lactobacillus Rhamnosus:
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155824/
  2. https://www.ncbi.nlm.nih.gov/pubmed/24299712
  1. https://www.ncbi.nlm.nih.gov/pubmed/26365389
  2. https://www.ncbi.nlm.nih.gov/pubmed/21899584
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844131/
  4. https://www.ncbi.nlm.nih.gov/pubmed/22692023
  5. https://www.ncbi.nlm.nih.gov/pubmed/22552453
  6. https://www.ncbi.nlm.nih.gov/pubmed/27596801
  7. https://www.ncbi.nlm.nih.gov/pubmed/23957340
  8. https://www.ncbi.nlm.nih.gov/pubmed/22702506
  9. https://www.ncbi.nlm.nih.gov/pubmed/26142892
  10. https://www.ncbi.nlm.nih.gov/pubmed/23740456

 

Bifidobacterium Breve:
  1. https://www.ncbi.nlm.nih.gov/pubmed/15491374
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1720633/
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048518/
  2. https://www.ncbi.nlm.nih.gov/pubmed/12598719
  3. https://www.ncbi.nlm.nih.gov/pubmed/16819382
  1. https://www.ncbi.nlm.nih.gov/pubmed/27590263
  2. https://www.ncbi.nlm.nih.gov/pubmed/15269618
  3. https://academic.oup.com/ajcn/article/93/1/81/4597712
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084046/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034291/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965514/

 

Bifidobacterium Coagulans:
  1. https://www.ncbi.nlm.nih.gov/pubmed/25079465
  2. https://www.ncbi.nlm.nih.gov/pubmed/24271261
  3. https://www.ncbi.nlm.nih.gov/pubmed/2079358
  4. https://www.ncbi.nlm.nih.gov/pubmed/2086441
  5. https://www.ncbi.nlm.nih.gov/pubmed/23786900
  6. https://www.ncbi.nlm.nih.gov/pubmed/26430929
  7. https://www.ncbi.nlm.nih.gov/pubmed/24706266
  8. https://www.ncbi.nlm.nih.gov/pubmed/25196301
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826289/
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947834/
  2. https://www.ncbi.nlm.nih.gov/pubmed/25219857
  3. https://academic.oup.com/jn/article/145/7/1446/4589930
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784472/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285933/
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443394/
  7. https://www.tandfonline.com/doi/full/10.1080/09168451.2014.972331
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724383/
  9. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769834/
  10. https://www.ncbi.nlm.nih.gov/pubmed/20140275
  11. https://www.ncbi.nlm.nih.gov/pubmed/19332970
  12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129566/
  13. https://www.ncbi.nlm.nih.gov/pubmed/24867512
  14. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460128/

 

Bifidobacterium infantis:
  1. https://www.nature.com/articles/pr2004591
  2. https://academic.oup.com/femspd/article/66/3/353/577227
  3. https://www.ncbi.nlm.nih.gov/pubmed/23192454
  1. https://www.ncbi.nlm.nih.gov/pubmed/20460726
  2. https://www.ncbi.nlm.nih.gov/pubmed/17189085
  3. https://gut.bmj.com/content/61/3/354
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744517/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744517/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774839/
  4. https://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.47306-0#tab2
  5. https://www.ncbi.nlm.nih.gov/pubmed/17893165
  6. https://www.ncbi.nlm.nih.gov/pubmed/19291170
  7. https://academic.oup.com/femspd/article/55/3/324/496928
  8. https://www.ncbi.nlm.nih.gov/pubmed/17259812
  9. https://www.ncbi.nlm.nih.gov/pubmed/16689181
  10. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997396/
  11. https://www.ncbi.nlm.nih.gov/pubmed/19367213
  12. https://www.ncbi.nlm.nih.gov/pubmed/16863564
  13. https://www.ncbi.nlm.nih.gov/pubmed/26418574
  14. https://www.ncbi.nlm.nih.gov/pubmed/25794930

 

Bifidobacterium Lactis (Note: was called “Bifidobacterium animalis in older studies”):
  1. https://www.sciencedirect.com/science/article/abs/pii/S089990071500461X?via%3Dihub
  2. https://www.nature.com/articles/pr2008218?proof=true&draft=journal
  3. https://www.ncbi.nlm.nih.gov/pubmed/18801055
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265429/
  5. https://www.ncbi.nlm.nih.gov/pubmed/16794305
  6. https://www.ncbi.nlm.nih.gov/pubmed/19236549
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171707/
  8. https://www.ncbi.nlm.nih.gov/pubmed/26268077
  9. https://www.ncbi.nlm.nih.gov/pubmed/19622191
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877827/
  2. https://www.ncbi.nlm.nih.gov/pubmed/15076628
  3. https://www.ncbi.nlm.nih.gov/pubmed/25599772
  4. https://www.ncbi.nlm.nih.gov/pubmed/15815206
  5. https://www.ncbi.nlm.nih.gov/pubmed/24322191
  6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761588/
  7. https://www.ncbi.nlm.nih.gov/pubmed/22284965
  8. https://www.ncbi.nlm.nih.gov/pubmed/17635382
  9. https://www.ncbi.nlm.nih.gov/pubmed/18801055

 

Bifidobacterium Longum:

151.https://www.ncbi.nlm.nih.gov/pubmed/15347767

  1. https://www.ncbi.nlm.nih.gov/pubmed/23192454
  2. https://academic.oup.com/femspd/article/66/3/353/577227
  3. https://www.ncbi.nlm.nih.gov/pubmed/22052061
  4. https://www.ncbi.nlm.nih.gov/pubmed/20460726
  5. https://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.47306-0
  6. https://www.ncbi.nlm.nih.gov/pubmed/19291170
  7. https://www.ncbi.nlm.nih.gov/pubmed/17259812
  8. https://www.ncbi.nlm.nih.gov/pubmed/24774670
  9. https://www.ncbi.nlm.nih.gov/pubmed/12906063
  10. https://www.ncbi.nlm.nih.gov/pubmed/16863564
  11. https://www.ncbi.nlm.nih.gov/pubmed/19367213

 

Saccharomyces Boulardii:
  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296087/
  2. https://www.ncbi.nlm.nih.gov/pubmed/25653151
  3. https://www.ncbi.nlm.nih.gov/pubmed/15858959
  4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125647/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829915/
  6. https://www.ncbi.nlm.nih.gov/pubmed/21997865
  7. https://www.ncbi.nlm.nih.gov/pubmed/18256417
  8. https://www.ncbi.nlm.nih.gov/pubmed/17306006
  9. https://www.ncbi.nlm.nih.gov/pubmed/27283364
  10. https://www.ncbi.nlm.nih.gov/pubmed/22476321
  11. https://www.ncbi.nlm.nih.gov/pubmed/22335323
  12. https://www.ncbi.nlm.nih.gov/pubmed/26216624
  13. https://www.ncbi.nlm.nih.gov/pubmed/7872284
  14. https://www.ncbi.nlm.nih.gov/pubmed/24311316
  15. https://www.ncbi.nlm.nih.gov/pubmed/15740542
  1. https://www.ncbi.nlm.nih.gov/pubmed/16572062
  2. https://www.ncbi.nlm.nih.gov/pubmed/15357564
  3. https://www.ncbi.nlm.nih.gov/pubmed/2494098
  4. https://www.ncbi.nlm.nih.gov/pubmed/7872284
  1. https://www.ncbi.nlm.nih.gov/pubmed/7872284

 

Streptococcus Thermophilus:
  1. https://www.ncbi.nlm.nih.gov/pubmed/14627358
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034325/
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526857/

 

Clinical Trial References for FEM PRO Formulation

At Doctors Pick, we only formulate nutritional products based on solid clinical evidence of potential benefits to you. Below is a list of the clinical trials, almost all on human participants, used as the basis for formulating FEM PRO.

References

Lactobacillus Acidophilus
1. https://www.cancer.gov/publications/dictionaries/cancer-drug/def/probiotic-acidophilus
2. https://www.ncbi.nlm.nih.gov/pubmed/8551535
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847857/
4. https://www.ncbi.nlm.nih.gov/pubmed/23747589
5. https://www.ncbi.nlm.nih.gov/pubmed/10067658
6. https://www.journalofdairyscience.org/article/S0022-0302(10)00545-X/fulltext
7. https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)60601-7/fulltext

Lactobacillus Bulgaricus
8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705123/
9. https://www.ncbi.nlm.nih.gov/pubmed/21986509
10. https://www.ncbi.nlm.nih.gov/pubmed/20487575
11. https://www.ncbi.nlm.nih.gov/pubmed/22923109
12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680912/
13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475728/
14. https://www.ncbi.nlm.nih.gov/pubmed/8432622
15. https://www.ncbi.nlm.nih.gov/pubmed/10660098
16. https://www.ncbi.nlm.nih.gov/pubmed/597607
17. https://www.ncbi.nlm.nih.gov/pubmed/3564372

Lactobacillus Casei:
18. https://www.ncbi.nlm.nih.gov/pubmed/26419583
19. https://www.ncbi.nlm.nih.gov/pubmed/26689231
20. https://www.ncbi.nlm.nih.gov/pubmed/24673738
21. https://www.ncbi.nlm.nih.gov/pubmed/20838859
22. https://www.ncbi.nlm.nih.gov/pubmed/21810608
23. https://www.ncbi.nlm.nih.gov/pubmed/26672414
24. https://www.ncbi.nlm.nih.gov/pubmed/22505595
25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743185/
26. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744000/
26. https://www.ncbi.nlm.nih.gov/pubmed/23992486
28. https://www.ncbi.nlm.nih.gov/pubmed/21329565
29. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858332/
30. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160870/#B55

Lactobacillus Fermentum:
31. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670518/
32. https://onlinelibrary.wiley.com/doi/abs/10.1002/jsfa.4214
33. https://www.ncbi.nlm.nih.gov/pubmed/21218486
34. https://www.sciencedirect.com/science/article/abs/pii/S0899900707000111?via%3Dihub
35. https://www.ncbi.nlm.nih.gov/pubmed/27447674
36. https://www.karger.com/Article/Abstract/328512
37. https://bjsm.bmj.com/content/44/4/222

Lactobacillus Gasseri:
38. https://www.ncbi.nlm.nih.gov/pubmed/20216555
39. https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effect-of-lactobacillus-gasseri-sbt2055-in-fermented-milk-on-abdominal-adiposity-in-adults-in-a-randomised-controlled-trial/304E3E2EE11E0D3D4F5D85E7046118A1
40. Kadooka Y et al. Effect of Lactobacillus gasseri SBT2055 in fermented milk on abdominal adiposity in adults in a randomized controlled trial. Br J Nutr. 2013 Nov 14;110(9):1696-703.Epub 2013 Apr 25
41. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391304/
42. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611107/
43. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391304/
44. Miyoshi M et al. Anti-obesity effect of Lactobacillus gasseri SBT2055 accompanied by inhibition of pro-inflammatory gene expression in the visceral adipose tissue in diet-induced obese mice.Eur J Nutr. 2014;53(2):599-606. doi: 10.1007/s00394-013-0568-9. Epub 2013 Aug 6.
45. https://link.springer.com/article/10.1007%2Fs00203-015-1101-8
46. https://www.wageningenacademic.com/doi/10.3920/BM2014.0108

Lactobacillus Helveticus:
47. https://www.ncbi.nlm.nih.gov/pubmed/20974015
48. https://www.researchgate.net/publication/282244005_Administration_of_Lactobacillus_helveticus_NS8_improves_behavioral_cognitive_and_biochemical_aberrations_caused_by_chronic_restraint_stress

Lactobacillus Plantarum:
49. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594053/
50. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419998/
51. https://www.researchgate.net/publication/304663353_Immunomodulatory_Effects_of_Lactobacillus_plantarum_Lp62_on_Intestinal_Epithelial_and_Mononuclear_Cells
52. https://www.ncbi.nlm.nih.gov/pubmed/25598393
53. https://www.ncbi.nlm.nih.gov/pubmed/26620542
54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882673/
55. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936756/

Lactobacillus Reuteri:
56. https://www.nature.com/articles/ejcn2012126
57. https://www.ncbi.nlm.nih.gov/pubmed/22067612
58. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917019/
59. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1348-0421.2009.00154.x
60. https://www.ncbi.nlm.nih.gov/pubmed/25688886
61. https://www.nature.com/articles/ejcn2012126
62. https://www.ncbi.nlm.nih.gov/pubmed/25531996
63. https://www.ncbi.nlm.nih.gov/pubmed/15629974
64. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813596/
65. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219330/
66. https://www.omicsonline.org/open-access/beneficial-bacteria-stimulate-youthful-thyroid-gland-activity-2165-7904.1000220.php?aid=26919
67. https://www.ncbi.nlm.nih.gov/pubmed/19895848

Lactobacillus Rhamnosus:
68. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155824/
69. https://www.ncbi.nlm.nih.gov/pubmed/24299712
70. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239510/
71. https://www.ncbi.nlm.nih.gov/pubmed/26365389
72. https://www.ncbi.nlm.nih.gov/pubmed/21899584
73. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844131/
74. https://www.ncbi.nlm.nih.gov/pubmed/22692023
75. https://www.ncbi.nlm.nih.gov/pubmed/22552453
76. https://www.ncbi.nlm.nih.gov/pubmed/27596801
77. https://www.ncbi.nlm.nih.gov/pubmed/23957340
78. https://www.ncbi.nlm.nih.gov/pubmed/22702506
79. https://www.ncbi.nlm.nih.gov/pubmed/26142892
80. https://www.ncbi.nlm.nih.gov/pubmed/23740456

Bifidobacterium bifidum:
81. https://www.ncbi.nlm.nih.gov/pubmed/27219886
82. https://www.ncbi.nlm.nih.gov/pubmed/27681077
83. https://www.ncbi.nlm.nih.gov/pubmed/28786012
84. https://www.ncbi.nlm.nih.gov/pubmed/28326881
85. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305430/
86. https://www.ncbi.nlm.nih.gov/pubmed/27209439
87. https://www.ncbi.nlm.nih.gov/pubmed/25604727
88. https://www.ncbi.nlm.nih.gov/pubmed/17878180
89. https://www.ncbi.nlm.nih.gov/pubmed/25909149
90. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133134/
91. https://www.ncbi.nlm.nih.gov/pubmed/22205338
92. https://www.ncbi.nlm.nih.gov/pubmed/25648808
93. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570661/
94. https://www.ncbi.nlm.nih.gov/pubmed/25244414
95. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630703/
96. https://www.ncbi.nlm.nih.gov/pubmed/15829425
97. https://www.ncbi.nlm.nih.gov/pubmed/27623957
98. https://www.ncbi.nlm.nih.gov/pubmed/1597660
99. https://www.ncbi.nlm.nih.gov/pubmed/21418261
100. https://www.ncbi.nlm.nih.gov/pubmed/18785988
101. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874795/

Bifidobacterium Breve:
102. https://www.ncbi.nlm.nih.gov/pubmed/15491374
103. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1720633/
104. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048518/
105. https://www.ncbi.nlm.nih.gov/pubmed/12598719
106. https://www.ncbi.nlm.nih.gov/pubmed/16819382
107. https://www.ncbi.nlm.nih.gov/pubmed/27590263
108. https://www.ncbi.nlm.nih.gov/pubmed/15269618
109. https://academic.oup.com/ajcn/article/93/1/81/4597712
110. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084046/
111. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034291/
112. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965514/

Bifidobacterium Coagulans:
113. https://www.ncbi.nlm.nih.gov/pubmed/25079465
114. https://www.ncbi.nlm.nih.gov/pubmed/24271261
115. https://www.ncbi.nlm.nih.gov/pubmed/2079358
116. https://www.ncbi.nlm.nih.gov/pubmed/2086441
117. https://www.ncbi.nlm.nih.gov/pubmed/23786900
118. https://www.ncbi.nlm.nih.gov/pubmed/26430929
119. https://www.ncbi.nlm.nih.gov/pubmed/24706266
120. https://www.ncbi.nlm.nih.gov/pubmed/25196301
121. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826289/
122. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947834/
123. https://www.ncbi.nlm.nih.gov/pubmed/25219857
124. https://academic.oup.com/jn/article/145/7/1446/4589930
125. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784472/
126. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285933/
127. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443394/
128. https://www.tandfonline.com/doi/full/10.1080/09168451.2014.972331
129. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724383/
130. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769834/
131. https://www.ncbi.nlm.nih.gov/pubmed/20140275
132. https://www.ncbi.nlm.nih.gov/pubmed/19332970
133. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129566/
134. https://www.ncbi.nlm.nih.gov/pubmed/24867512
135. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460128/

Bifidobacterium infantis:
136. https://www.nature.com/articles/pr2004591
137. https://academic.oup.com/femspd/article/66/3/353/577227
138. https://www.ncbi.nlm.nih.gov/pubmed/23192454
139. https://www.ncbi.nlm.nih.gov/pubmed/20460726
140. https://www.ncbi.nlm.nih.gov/pubmed/17189085
141. https://gut.bmj.com/content/61/3/354
142. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744517/
143. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744517/
144. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774839/
145. https://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.47306-0#tab2
146. https://www.ncbi.nlm.nih.gov/pubmed/17893165
147. https://www.ncbi.nlm.nih.gov/pubmed/19291170
148. https://academic.oup.com/femspd/article/55/3/324/496928
149. https://www.ncbi.nlm.nih.gov/pubmed/17259812
150. https://www.ncbi.nlm.nih.gov/pubmed/16689181
151. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997396/
152. https://www.ncbi.nlm.nih.gov/pubmed/19367213
153. https://www.ncbi.nlm.nih.gov/pubmed/16863564
154. https://www.ncbi.nlm.nih.gov/pubmed/26418574
155. https://www.ncbi.nlm.nih.gov/pubmed/25794930

Bifidobacterium Lactis (Note: was called “Bifidobacterium animalis in older studies”):
156. https://www.sciencedirect.com/science/article/abs/pii/S089990071500461X?via%3Dihub
157. https://www.nature.com/articles/pr2008218?proof=true&draft=journal
158. https://www.ncbi.nlm.nih.gov/pubmed/18801055
159. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265429/
160. https://www.ncbi.nlm.nih.gov/pubmed/16794305
161. https://www.ncbi.nlm.nih.gov/pubmed/19236549
162. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171707/
163. https://www.ncbi.nlm.nih.gov/pubmed/26268077
164. https://www.ncbi.nlm.nih.gov/pubmed/19622191
165. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877827/
166. https://www.ncbi.nlm.nih.gov/pubmed/15076628
167. https://www.ncbi.nlm.nih.gov/pubmed/25599772
168. https://www.ncbi.nlm.nih.gov/pubmed/15815206
169. https://www.ncbi.nlm.nih.gov/pubmed/24322191
170. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761588/
171. https://www.ncbi.nlm.nih.gov/pubmed/22284965
172. https://www.ncbi.nlm.nih.gov/pubmed/17635382
173. https://www.ncbi.nlm.nih.gov/pubmed/18801055

Bifidobacterium Longum:
174. https://www.ncbi.nlm.nih.gov/pubmed/15347767
175. https://www.ncbi.nlm.nih.gov/pubmed/23192454
176. https://academic.oup.com/femspd/article/66/3/353/577227
177. https://www.ncbi.nlm.nih.gov/pubmed/22052061
178. https://www.ncbi.nlm.nih.gov/pubmed/20460726
178. https://jmm.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.47306-0
180. https://www.ncbi.nlm.nih.gov/pubmed/19291170
181. https://www.ncbi.nlm.nih.gov/pubmed/17259812
182. https://www.ncbi.nlm.nih.gov/pubmed/24774670
183. https://www.ncbi.nlm.nih.gov/pubmed/12906063
184. https://www.ncbi.nlm.nih.gov/pubmed/16863564
185. https://www.ncbi.nlm.nih.gov/pubmed/19367213

Bacillus Subtilis:
186. https://www.ncbi.nlm.nih.gov/pubmed/23328284
187. https://www.microbiologyresearch.org/content/journal/jmmcr/10.1099/jmmcr.0.004036
188. DOI: https://doi.org/10.1016/j.celrep.2019.12.078

Saccharomyces Boulardii:
189. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296087/
190. https://www.ncbi.nlm.nih.gov/pubmed/25653151
191. https://www.ncbi.nlm.nih.gov/pubmed/15858959
192. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125647/
193. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829915/
194. https://www.ncbi.nlm.nih.gov/pubmed/21997865
195. https://www.ncbi.nlm.nih.gov/pubmed/18256417
196. https://www.ncbi.nlm.nih.gov/pubmed/17306006
197. https://www.ncbi.nlm.nih.gov/pubmed/27283364
198. https://www.ncbi.nlm.nih.gov/pubmed/22476321
199. https://www.ncbi.nlm.nih.gov/pubmed/22335323
200. https://www.ncbi.nlm.nih.gov/pubmed/26216624
201. https://www.ncbi.nlm.nih.gov/pubmed/7872284
202. https://www.ncbi.nlm.nih.gov/pubmed/24311316
203. https://www.ncbi.nlm.nih.gov/pubmed/15740542
204. https://www.ncbi.nlm.nih.gov/pubmed/16572062
205. https://www.ncbi.nlm.nih.gov/pubmed/15357564
206. https://www.ncbi.nlm.nih.gov/pubmed/2494098
207. https://www.ncbi.nlm.nih.gov/pubmed/7872284
208. https://www.frontiersin.org/articles/10.3389/fnagi.2016.00256/full

Saffron:
209: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599112/
210: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643654/
211. https://www.ncbi.nlm.nih.gov/pubmed/27595298
212. https://www.ncbi.nlm.nih.gov/pubmed/15707766
213. https://obgyn.onlinelibrary.wiley.com/doi/full/10.1111/j.1471-0528.2007.01652.x
214. https://www.ncbi.nlm.nih.gov/pubmed/19720342
215. https://www.ncbi.nlm.nih.gov/pubmed/20831681
216. https://www.ncbi.nlm.nih.gov/pubmed/19838862
217. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941716/
218. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850693/
219. https://www.ncbi.nlm.nih.gov/pubmed/20688744
220. https://www.ncbi.nlm.nih.gov/pubmed/30343354

Inubio™ Prebiotic Ingredients—Inulin, Chicory Root & Jerusalem Artichoke:
221. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686634/
222. https://www.ncbi.nlm.nih.gov/pubmed/28596023?dopt=Abstract
223. ttps://academic.oup.com/jn/search-results?f_TocHeadingTitle=Inulin%20and%20Oligofructose:%20Health%20Benefits%20and%20Claims-A%20Critical%20Review
224. https://academic.oup.com/jn/article/137/11/2524S/4664499
225. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705355/
226. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896694/
227. https://www.ncbi.nlm.nih.gov/pubmed/24688953
228. https://www.ncbi.nlm.nih.gov/pubmed/18853230
229. https://www.ncbi.nlm.nih.gov/pubmed/27623982
230. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041804/